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This Concept Map, created with IHMC CmapTools, has information related to: Ulcerative Colitis vs Crohns Disease, Crohn's Disease Chronic, relapsing inflammatory disorder affecting the gastrointestinal tract Location Small intestines, Ulcerative Colitis Chronic inflammatory bowel disorderof the mucosa & submucosa of the colon & rectum Manifestations Fatigue Anemia Anorexia Weight loss High pitched bowel sounds Abdominal pain & cramping, Ulcerative Colitis Chronic inflammatory bowel disorderof the mucosa & submucosa of the colon & rectum Course of Disease Chronic Intermittent, Crohn's Disease Chronic, relapsing inflammatory disorder affecting the gastrointestinal tract Pathophysiology Usually involves terminal illeum and ascending colon Begins with a small inflammatory aphthoid lesion then forms deeper ulcerations, granulomatous lessions, and fissures Fibrotic changes thicken can lead to local obstruction abscess and fistula formations Malnutrition and malabsorption occurs, Crohn's Disease Chronic, relapsing inflammatory disorder affecting the gastrointestinal tract Complications Obstruction Fistulas Abscess formation Malabsorption, Ulcerative Colitis Chronic inflammatory bowel disorderof the mucosa & submucosa of the colon & rectum Diarrhea Relieved by defication, Crohn's Disease Chronic, relapsing inflammatory disorder affecting the gastrointestinal tract Diarrhea Relieved by defication, Arthritis Skin/Mucous Membrane lesions Uveitis Weakness Rectal inflammation LLQ cramps relieved by defication Contains blood & mucus Fever Manifestations Fatigue Anemia Anorexia Weight loss High pitched bowel sounds Abdominal pain & cramping, Crohn's Disease Chronic, relapsing inflammatory disorder affecting the gastrointestinal tract Diarrhea 5 Loose stools/day No obvious blood or mucus Persistent diarrhea, Ulcerative Colitis Chronic inflammatory bowel disorderof the mucosa & submucosa of the colon & rectum Pathophysiology Begins at rectum and progresses proximally Crypt abscesses form Mucosa becomes red & edematous d/t vascular congestion, friable, & ulcerated Bleeds easily Hemorrhage is common Chronic inflammation leads to atrophy & narrowing, Crohn's Disease Chronic, relapsing inflammatory disorder affecting the gastrointestinal tract Manifestations Fatigue Anemia Anorexia Weight loss High pitched bowel sounds Abdominal pain & cramping, Malaise Abdominal pain & tenderness RLQ or periumbilical pain Does not contain blood Streatorrhea Manifestations Fatigue Anemia Anorexia Weight loss High pitched bowel sounds Abdominal pain & cramping, Crohn's Disease Chronic, relapsing inflammatory disorder affecting the gastrointestinal tract Appearance Cobblestone appearnace Areas of normal tissue surrounded by ulcerations & fissures, Obstruction Fistulas Abscess formation Malabsorption ???? Colorectal Cancer, Toxic Megacolon Perforation Massive Hemorrhage ???? Colorectal Cancer, Ulcerative Colitis Chronic inflammatory bowel disorderof the mucosa & submucosa of the colon & rectum Compiications Toxic Megacolon Perforation Massive Hemorrhage, Crohn's Disease Chronic, relapsing inflammatory disorder affecting the gastrointestinal tract Course of Disease Slowly Relapsing, Ulcerative Colitis Chronic inflammatory bowel disorderof the mucosa & submucosa of the colon & rectum Appearance Granular Dull Hyperemic Uniform in affected bowel Pseudopolyps my be seen, Ulcerative Colitis Chronic inflammatory bowel disorderof the mucosa & submucosa of the colon & rectum Location Large Bowel, Ulcerative Colitis Chronic inflammatory bowel disorderof the mucosa & submucosa of the colon & rectum Diarrhea Up to 5-30 stools/day Rectal bleeding Mucus may be present