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This Concept Map, created with IHMC CmapTools, has information related to: Diabetes insipidus, DI S/S Increased serum osmolality -hypernatremia, DI types Neurogenic- problem with ADH synth or release, Dec. instravascular fluid volume leading to Increased serum osmolality -hypernatremia, ADH given neurogenic if urine osmolality rises > 9%, ADH given nephrogenic No response, nephrogenic- inadequate renal response to ADH TX Low Na diet Thiazide diuretics (slows filtration rate & allows kidneys to absorb more h2o), Deficiency in production or secretion of ADH Dec water reabsorption in renal tubules, Increased serum osmolality -hypernatremia Tacchycardia & hypertension, Fluids withheld for 8-16 hours. Test stops when urine osmolality stabalizes for 3 hours ADH given, Neurogenic- problem with ADH synth or release TX Hormone replacement(DDAVP) Fluid replacement (Hypotonic saline or D5W), Dec water reabsorption in renal tubules Dec. instravascular fluid volume, DI patho Deficiency in production or secretion of ADH, Water deprivation Test Fluids withheld for 8-16 hours. Test stops when urine osmolality stabalizes for 3 hours, DI DX Water deprivation Test, DI types nephrogenic- inadequate renal response to ADH, DI S/S Excessive urine output, Dec. instravascular fluid volume leading to Excessive urine output, DI types psychogenic- excessive h2o intake (can by psych or lesion in thirst center), psychogenic- excessive h2o intake (can by psych or lesion in thirst center) TX counseling tx for hypervolemia