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This Concept Map, created with IHMC CmapTools, has information related to: diabetes type 1, Failure to produce insulin causes Production of excess glucagon, Failure to produce insulin leads to elevated blood glucose, gluconeogenesis: production of glucose from non carb sources- fats and proteins causing inc ketones, Inc. serum osmolarity body tries to flush glucose, causing polyuria, elevated blood glucose can lead to chronic elevations of blood glucose, acidosis DKA, Genetic predisposition Environmental stressor 1A-autoimmune 1B- unk etiology leading to destruction of beta cells, inc ketones Fruity breath, Inc. serum osmolarity body tries to flush glucose, causing polydipsia, wasting of lean body mass causing fatigue, Production of excess glucagon leads to gluconeogenesis: production of glucose from non carb sources- fats and proteins, Type 1 Diabetes Caused by Genetic predisposition Environmental stressor 1A-autoimmune 1B- unk etiology, no glucose for energy causing polyphagia, Failure to produce insulin leads to no glucose for energy, elevated blood glucose causing Inc. serum osmolarity, destruction of beta cells leads to Failure to produce insulin, wasting of lean body mass causing weight loss, inc ketones acidosis, gluconeogenesis: production of glucose from non carb sources- fats and proteins leads to wasting of lean body mass