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This Concept Map, created with IHMC CmapTools, has information related to: acromegaly, Inhibits GH by increasing GHIH. COSTLY. somatostatins, specifically, octreotide (sandostatin), Acromegaly Treatment (80% req. multiple tx) Radiation: May take 5-10 years often needs HRT for life, history/physical IGF test Oral GTT, MRI CT Eye exam IGF- (insulin like growth factor) more accurate than a serum GH, Acromegaly Treatment (80% req. multiple tx) Drugs: to red. GH, Drugs: to red. GH types somatostatins, specifically, octreotide (sandostatin), Acromegaly diagnosis history/physical IGF test Oral GTT, MRI CT Eye exam, Drugs: to red. GH types dopamine Agonist cabergoline (dostinex). may be used as first line, not as effective, but cheaper., Acromegaly Treatment (80% req. multiple tx) surgery: hypophysectomy., Acromegaly S/S Enlarged hands and feet thickening and enlargement of face and head bony and soft tissue, sleep apnea, Signs of DM, cardiomegaly, peripheral neuropathy, hyperglycemia, and hypertension, history/physical IGF test Oral GTT, MRI CT Eye exam GH levels normally fall during GTT. If not, + for acromegaly, Drugs: to red. GH types GH receptor Agonist: Not a first line agent. used if poor response to surgery/radiation, blocks effects of GH GH receptor Agonist: Not a first line agent. used if poor response to surgery/radiation, An excess of GH which can be caused by: Benign pit tumor, Excessive GH secretion, Acromegaly results from An excess of GH