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This Concept Map, created with IHMC CmapTools, has information related to: CBL A1 Back Pain, acute fx T-4 leads to inflammation, transcription factor stimulates production of osteoprotegerin, Betty VanCleef is underweight, IL-1 promote production of osteoclasts, Betty VanCleef admits high diet soda intake, Betty VanCleef is female, estrogen desensitizes bone, Betty VanCleef admits heavy tobacco use, parathyroid gland senses low levels of Calcium, IL-6 promote production of osteoclasts, osteoclasts contains carbonic anhydrase 2, Betty VanCleef is older than 50, Betty VanCleef admits no exercise, Osteoporosis characterized by low bone density, BMI = 17.5 indicates underweight, physical exam shows point tenderness @ T-4, COX-II enzymes ???? T cells, Betty VanCleef is prescribed NSAID, estrogen binds to estrogen receptor, BMD test measures low bone density