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This Concept Map, created with IHMC CmapTools, has information related to: Histology of the Esophagus and Stomach, Mucosa Muscularis mucosae, Lamina propria Connective tissue. May contain lymphatic nodules., Pyloric glands Located near the pyloric sphincter in the antrum of the stomach. Look very similar to cardiac glands because they too only secrete mucus to protect the duodenum from stomach acid. The only real difference is that the gastric pit is longer and the gland is slightly shorter than seen in cardiac glands. It is not uncommon to see an occasional parietal cell., Epithelium Non-keratinized stratified squamous, Parietal cell Found near the middle and bottom of gastric glands. Secrete HCl. Notice the collapsed canalicular system that, when rearranged, is where the H+/K+ ATP-powered pump extrudes acid into the lumen of the gland. These cells resemble fried eggs and stain red/pink., Mucosa Epithelium, Lamina propria Muscularis mucosae, Stomach Mucosa, Chief cell Found in the distal 1/2 to 1/3 of gastric glands. Secrete pepsinogen. Notice that the entire cytoplasm is full of zymogen granules. These cells stain intensely red when fixed properly (pepsinogen not washed out). The basal portion of these cells will stain purple while the apical region (contains zymogens) will stain a grainy red., Esophagus Submucosa, Mucosa Lamina propria, Mucus cell Line the stomach and secrete mucus to protect the epithelium from damage due to the acidic environment. Notice the apically located mucus-containing granules, Gastroesophageal junction* Stomach, Epithelium Lamina propria, 3 different types of glands Fundic (gastric) glands, Serosa/adventitia Serosa = visceral pleura, when not connected to anything else. Serosa is present on the abdominal esophagus but not proximal, Muscularis mucosae One or two layers of smooth muscle., 5 different cell types Enteroendocrine cell, Stomach Serosa/adventitia, Histology of the Esophagus and Stomach Esophagus