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This Concept Map, created with IHMC CmapTools, has information related to: 5-Asthma, treated for asthma and allergy symptoms medications include Albuterol MDI: 2 puffs prn acute problems (uses 2-10 times daily, avg 6 doses/day), triggered by exercise, Intrinsic (Non-Atopic) Symptoms include No allergen identified, Low serum IgE, Late onset, Chronic, H1 receptor smooth muscle cells constriction of bronchiole smooth muscle, History 2 or more of these +/- conjunctivitis, social history unable to work uncontrolled asthma and rhinitis (previously worked for Rockingham county fixing roads) so lost health insurance, Oral Decongestant use not recommended, H2 receptor stomach mucousal cells stomach acid production, Extrinsic (Atopic) Predisposed to developing Asthma, Pre-albuterol FEV1 (38%) FVC (72%) 53%, triggered by stress, Allergic responses causing Airway hyperreactivity and remodeling, Medical history 7 yo presented with asthma and allergy symptoms, Methylxanthines (theophyline) Physiological actions CNS, Dx: asthma and allergy ???? diagnostic test, 53% ???? moderate obstructive defect, Mast Cell Stablizier Mechanism of action Blocks calcium channel which enabes the release of histamine, Antihistamines Mechanism of action Inhibits the binding of histamines to the receptor site; however histamine still released, Pathophysiology i Recognition of allergen leading to release of cytokines, leukotrienes, and histamine by mast cells and TH2 cells, Extrinsic (Atopic) Predisposed to developing Allergic Rhinitis