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This Concept Map, created with IHMC CmapTools, has information related to: Map 6, P2Y12 inhibitor (Ticagrelor) ???? Adverse effects, -COX2 Inhibitors (Aspirin) -Glycoprotein lib/IIIa inhibitors -P2Y12 inhibitors (Ticagrelor) Case Drug P2Y12 inhibitor (Ticagrelor), Endothelial Dysfunction Role In Pathophysiology Of Vascular Diseases Arterial & Venous Disease, and Thrombosis Arterial Disease, 54 YOM, Wt 250lbs Symptoms Decreased Feeling in Toes, Antiplatelet Agents Drugs -COX2 Inhibitors (Aspirin) -Glycoprotein lib/IIIa inhibitors -P2Y12 inhibitors (Ticagrelor), 2PPD for 30 yrs Moved down to 1PPD, Endothelial Dysfunction Role In Pathophysiology Of Vascular Diseases Endothelium Dysfunction Dysglycemia, 54 YOM, Wt 250lbs Current Medications Add Ticagrelor, Venous Disease is diagnosed by, Endothelial Dysfunction Role In Pathophysiology Of Vascular Diseases Arterial & Venous Disease, and Thrombosis Virchows Triad, Fish Oil ???? May increase the risk of bleeding when taking with Ticagrelor, Aspirin ???? Can decrease effectiveness of Ticagrelor if more than 100mg is administered, 54 YOM, Wt 250lbs Current Medications Asks about Fish Oil, Leads to ???? Foam Cell Formation, Dyslipidemia Drugs -Statins (Atorvastatin) -Fibrates -PCSK9 inhibitors -Fish oil, 54 YOM, Wt 250lbs Current Medications Metformin 500 mg BID, 54 YOM, Wt 250lbs Requests Help Finding a Doctor, 54 YOM, Wt 250lbs Current Medications Warfarin 5 mg qd, Substrates ???? CYP3A4/5, Adverse effects ???? Renal