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This Concept Map, created with IHMC CmapTools, has information related to: Patient Case - Case Recitation, Nausea and Motion Sickness Likely cause Increased anticholinergic activity attributed to Amitriptyline and perhaps Zyrtec, Wants to treat Nausea/Motion Sickness Clinical Presentations Blood Pressure: 130/85 Heart Rate: 95, 68 YOWF Chronic Illnesses Neurogenic Pain/Sleep Problems, Decreased Cognitive Ability Likely cause Increased anticholinergic activity attributed to Amitriptyline and perhaps Zyrtec, 68 YOWF Clinical Presentations Decreased Cognitive Ability, How long have you been on these medications? What is your diet like? What does your blood pressure/HR usually run? All of the Intro to Pharmacy Pratice questions: do you smoke? drink? exercise etc Have you had any falls or fractures recently? Depression assessment questions (precautionary) Recommendations No Dramamine - also on Beer's list Consult with prescriber to consider alternative therapy for amitriptyline and zyrtec. MUST FIND ALTERNATIVES TO ANTICHOLINERGIC DRUGS, Muscarinic Receptor Antagonist M3 Receptor Dry Eyes, 68 YOWF Clinical Presentations Blood Pressure: 130/85 Heart Rate: 95, Wants to treat Nausea/Motion Sickness Clinical Presentations Constipation, 68 YOWF Cholinergic Activity Normal Cholinergic Function, 68 YOWF Clinical Presentations Nausea and Motion Sickness, Amitriptyline 50mg (anticholinergic drug, on Beer's list) Drug Characteristics Tricyclic anti-depressant used for nerve pain and depression. High anticholinergic effects Placed on Beer's list, Wants to treat Nausea/Motion Sickness Clinical Presentations Dry Eyes, 68 YOWF How long have you been on these medications? What is your diet like? What does your blood pressure/HR usually run? All of the Intro to Pharmacy Pratice questions: do you smoke? drink? exercise etc Have you had any falls or fractures recently? Depression assessment questions (precautionary), Aleve (PRN use; likely 220mg) Drug Characteristics NSAID, Normal Cholinergic Function Normal Receptor Binding Lowers Blood Pressure, Normal Cholinergic Function Normal Receptor Binding ????, 68 YOWF Chronic Illnesses Allergies, Normal Cholinergic Function Normal Receptor Binding Bladder Contraction & Sphincter Relaxes, Wants to treat Nausea/Motion Sickness Clinical Presentations Decreased Cognitive Ability