WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: Untitled 1, pyridostigmine (mestinon) con's doesnt treat immune problem, Down regulation of receptor associated conditions Anticholinesterase Poisoning, Bombardment of nAChR with ACh which causes Twitching, ACh inhibitors which Increase ACh, Myasthenia Gravis treatment Edrephonium, Decrease nicotine receptor availability occurs via Bombardment of nAChR with ACh, Myasthenia Gravis symptoms fatigue, 68.2-102.2 milligrams of Succinylcholine Onset of Action 60-90 seconds, Competetive Inhibition For example Edrophonium, Neutralize the toxin of nicotinic effects by Cleaving the OP-acetyl cholinesterase complexes that are still not aged, Acetylcholinesterase Inhibition leads to Increased levels of Acetylcholine, Delayed (24h to 2 weeks) Nicotinic Receptor Action Intermediate syndrome, 30% of working dose for 1-2 Weeks, Organophosphates and Carbamate Poisioning Can be tested by Atropine Test, Acetylcholine acts on Ligand-gated Nicotinic Receptors, Atropine dosed intravenously 2-5 mg every 5 minutes doubling the initial dose, Block ACh release from nerve ending Botulinum Toxin By inhibiting contraction, 0.1 mg/kg IV if required for the reversal of muscle relaxation may repeat every 5 mins, Train of Four (TOF) 2 mechanisms Irreversibly, Block ACh binding to esterase 2 mechanisms Irreversibly