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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1949 2
1951 2
1952 1
1955 1
1957 1
1958 1
1959 1
1960 1
1964 3
1965 2
1966 1
1968 4
1969 3
1970 3
1971 3
1972 3
1973 3
1974 7
1975 4
1976 5
1977 1
1978 3
1979 7
1980 7
1981 5
1982 8
1983 14
1984 11
1985 11
1986 9
1987 14
1988 14
1989 22
1990 27
1991 32
1992 23
1993 37
1994 47
1995 40
1996 55
1997 62
1998 73
1999 76
2000 86
2001 105
2002 114
2003 133
2004 123
2005 195
2006 285
2007 345
2008 406
2009 509
2010 529
2011 567
2012 716
2013 846
2014 919
2015 1007
2016 994
2017 1022
2018 1060
2019 1085
2020 1222
2021 1329
2022 1196
2023 1078
2024 360

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15,097 results

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Page 1
Theories of pain: from specificity to gate control.
Moayedi M, Davis KD. Moayedi M, et al. J Neurophysiol. 2013 Jan;109(1):5-12. doi: 10.1152/jn.00457.2012. Epub 2012 Oct 3. J Neurophysiol. 2013. PMID: 23034364 Free article. Review.
Several theoretical frameworks have been proposed to explain the physiological basis of pain, although none yet completely accounts for all aspects of pain perception. Here, we provide a historical overview of the major contributions, ideas, and competing the …
Several theoretical frameworks have been proposed to explain the physiological basis of pain, although none yet completely accounts f …
Cognitive and emotional control of pain and its disruption in chronic pain.
Bushnell MC, Ceko M, Low LA. Bushnell MC, et al. Nat Rev Neurosci. 2013 Jul;14(7):502-11. doi: 10.1038/nrn3516. Epub 2013 May 30. Nat Rev Neurosci. 2013. PMID: 23719569 Free PMC article. Review.
Chronic pain is one of the most prevalent health problems in our modern world, with millions of people debilitated by conditions such as back pain, headache and arthritis. ...It will also examine the accumulating evidence that chronic pain itself alters brain …
Chronic pain is one of the most prevalent health problems in our modern world, with millions of people debilitated by conditions such …
Pain Perception and Management: Where do We Stand?
Afridi B, Khan H, Akkol EK, Aschner M. Afridi B, et al. Curr Mol Pharmacol. 2021;14(5):678-688. doi: 10.2174/1874467213666200611142438. Curr Mol Pharmacol. 2021. PMID: 32525788 Free PMC article. Review.
Neuropathic pain results in nerve damage. In inflammatory pain, inflammatory mediators are involved in the sensitization of nociceptors. ...RESULTS: With a better understanding of the physiological and chemical mechanisms that play a role in pain, significant …
Neuropathic pain results in nerve damage. In inflammatory pain, inflammatory mediators are involved in the sensitization of no …
Human brain mechanisms of pain perception and regulation in health and disease.
Apkarian AV, Bushnell MC, Treede RD, Zubieta JK. Apkarian AV, et al. Eur J Pain. 2005 Aug;9(4):463-84. doi: 10.1016/j.ejpain.2004.11.001. Epub 2005 Jan 21. Eur J Pain. 2005. PMID: 15979027 Free article. Review.
CONTEXT: The perception of pain due to an acute injury or in clinical pain states undergoes substantial processing at supraspinal levels. ...A meta-analysis highlights important methodological differences in identifying the brain network underlying acute p …
CONTEXT: The perception of pain due to an acute injury or in clinical pain states undergoes substantial processing at s …
Neuropathic cancer pain: prevalence, pathophysiology, and management.
Yoon SY, Oh J. Yoon SY, et al. Korean J Intern Med. 2018 Nov;33(6):1058-1069. doi: 10.3904/kjim.2018.162. Epub 2018 Jun 25. Korean J Intern Med. 2018. PMID: 29929349 Free PMC article. Review.
Neuropathic cancer pain (NCP) is caused by nerve damage attributable to the cancer per se, and/or treatments including chemotherapy, radiotherapy, and surgery; the prevalence is reported to be as high as 40%. ...This review addresses the pathophysiology, clinical character …
Neuropathic cancer pain (NCP) is caused by nerve damage attributable to the cancer per se, and/or treatments including chemotherapy, …
Exercise-Induced Hypoalgesia in Pain-Free and Chronic Pain Populations: State of the Art and Future Directions.
Rice D, Nijs J, Kosek E, Wideman T, Hasenbring MI, Koltyn K, Graven-Nielsen T, Polli A. Rice D, et al. J Pain. 2019 Nov;20(11):1249-1266. doi: 10.1016/j.jpain.2019.03.005. Epub 2019 Mar 21. J Pain. 2019. PMID: 30904519 Free article. Review.
In contrast, EIH is more variable in chronic pain populations and is more frequently impaired; with pain and pain sensitivity decreasing, remaining unchanged or, in some cases, even increasing in response to exercise. ...PERSPECTIVE: This article provides a c …
In contrast, EIH is more variable in chronic pain populations and is more frequently impaired; with pain and pain sensi …
Nociception, Pain, Negative Moods, and Behavior Selection.
Baliki MN, Apkarian AV. Baliki MN, et al. Neuron. 2015 Aug 5;87(3):474-91. doi: 10.1016/j.neuron.2015.06.005. Neuron. 2015. PMID: 26247858 Free PMC article. Review.
Recent neuroimaging studies suggest that the brain adapts with pain, as well as imparts risk for developing chronic pain. Within this context, we revisit the concepts for nociception, acute and chronic pain, and negative moods relative to behavior selection. …
Recent neuroimaging studies suggest that the brain adapts with pain, as well as imparts risk for developing chronic pain. With …
The Role of Sex Hormones in Pain-Related Conditions.
Athnaiel O, Cantillo S, Paredes S, Knezevic NN. Athnaiel O, et al. Int J Mol Sci. 2023 Jan 18;24(3):1866. doi: 10.3390/ijms24031866. Int J Mol Sci. 2023. PMID: 36768188 Free PMC article. Review.
For biological males, high levels of testosterone have shown to increase their pain threshold; and for biological females, estrogen fluctuations have shown to increase pain intensity and perception. However, sex hormones have not been studied in the context o …
For biological males, high levels of testosterone have shown to increase their pain threshold; and for biological females, estrogen f …
Prefrontal engrams of long-term fear memory perpetuate pain perception.
Stegemann A, Liu S, Retana Romero OA, Oswald MJ, Han Y, Beretta CA, Gan Z, Tan LL, Wisden W, Gräff J, Kuner R. Stegemann A, et al. Nat Neurosci. 2023 May;26(5):820-829. doi: 10.1038/s41593-023-01291-x. Epub 2023 Apr 6. Nat Neurosci. 2023. PMID: 37024573 Free PMC article.
A painful episode can lead to a life-long increase in an individual's experience of pain. Fearful anticipation of imminent pain could play a role in this phenomenon, but the neurobiological underpinnings are unclear because fear can both suppress and enhance pain …
A painful episode can lead to a life-long increase in an individual's experience of pain. Fearful anticipation of imminent pain …
A meta-analytic review of the hypoalgesic effects of exercise.
Naugle KM, Fillingim RB, Riley JL 3rd. Naugle KM, et al. J Pain. 2012 Dec;13(12):1139-50. doi: 10.1016/j.jpain.2012.09.006. Epub 2012 Nov 8. J Pain. 2012. PMID: 23141188 Free PMC article. Review.
The purpose of this article was to examine the effects of acute exercise on pain perception in healthy adults and adults with chronic pain using meta-analytic techniques. ...The results suggest that all 3 types of exercise reduce perception of experime …
The purpose of this article was to examine the effects of acute exercise on pain perception in healthy adults and adults with …
15,097 results
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