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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 4
1984 4
1985 4
1986 2
1987 6
1988 10
1989 6
1990 17
1991 10
1992 11
1993 17
1994 13
1995 12
1996 11
1997 16
1998 25
1999 18
2000 20
2001 17
2002 20
2003 19
2004 27
2005 22
2006 22
2007 34
2008 27
2009 24
2010 25
2011 29
2012 32
2013 38
2014 43
2015 52
2016 52
2017 50
2018 29
2019 23
2020 18
2021 36
2022 54
2023 37
2024 13

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875 results

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Quoted phrase not found in phrase index: "Human"
Page 1
Status epilepticus in the ICU.
Rossetti AO, Claassen J, Gaspard N. Rossetti AO, et al. Intensive Care Med. 2024 Jan;50(1):1-16. doi: 10.1007/s00134-023-07263-w. Epub 2023 Dec 20. Intensive Care Med. 2024. PMID: 38117319 Review.
SE that continues despite these medications is called refractory, and most commonly treated with continuous infusions of midazolam or propofol. Alternatives include further non-sedating ASM and non-pharmacologic approaches. SE that reemerges after weaning or continues desp …
SE that continues despite these medications is called refractory, and most commonly treated with continuous infusions of midazolam or …
Remimazolam for anaesthesia or sedation.
Sneyd JR, Rigby-Jones AE. Sneyd JR, et al. Curr Opin Anaesthesiol. 2020 Aug;33(4):506-511. doi: 10.1097/ACO.0000000000000877. Curr Opin Anaesthesiol. 2020. PMID: 32530890 Review.
SUMMARY: Remimazolam provides effective procedural sedation with superior success rates and recovery profile when compared to midazolam. Comparisons with propofol are required. Preliminary studies suggest potential for using remimazolam as the hypnotic component of general …
SUMMARY: Remimazolam provides effective procedural sedation with superior success rates and recovery profile when compared to midazolam …
Midazolam and other benzodiazepines.
Olkkola KT, Ahonen J. Olkkola KT, et al. Handb Exp Pharmacol. 2008;(182):335-60. doi: 10.1007/978-3-540-74806-9_16. Handb Exp Pharmacol. 2008. PMID: 18175099 Review.
The four benzodiazepines, widely used in clinical anaesthesia, are the agonists midazolam, diazepam and lorazepam and the antagonist flumazenil. Midazolam, diazepam and flumazenil are metabolized by cytochrome P450 (CYP) enzymes and by glucuronide conjugation wherea …
The four benzodiazepines, widely used in clinical anaesthesia, are the agonists midazolam, diazepam and lorazepam and the antagonist …
Sedation outcomes for remimazolam, a new benzodiazepine.
Oka S, Satomi H, Sekino R, Taguchi K, Kajiwara M, Oi Y, Kobayashi R. Oka S, et al. J Oral Sci. 2021 Jun 29;63(3):209-211. doi: 10.2334/josnusd.21-0051. Epub 2021 Jun 7. J Oral Sci. 2021. PMID: 34092775 Free article. Review.
Onset time from drug administration to optimal sedation level was faster for remimazolam (around 1.5-6.4 min) than for midazolam. Recovery time was significantly shorter for remimazolam than for midazolam and propofol. A study comparing various doses of remimazolam …
Onset time from drug administration to optimal sedation level was faster for remimazolam (around 1.5-6.4 min) than for midazolam. Rec …
Benzodiazepines in the Management of Seizures and Status Epilepticus: A Review of Routes of Delivery, Pharmacokinetics, Efficacy, and Tolerability.
Kienitz R, Kay L, Beuchat I, Gelhard S, von Brauchitsch S, Mann C, Lucaciu A, Schäfer JH, Siebenbrodt K, Zöllner JP, Schubert-Bast S, Rosenow F, Strzelczyk A, Willems LM. Kienitz R, et al. CNS Drugs. 2022 Sep;36(9):951-975. doi: 10.1007/s40263-022-00940-2. Epub 2022 Aug 16. CNS Drugs. 2022. PMID: 35971024 Free PMC article. Review.
Although all BZDs act as allosteric modulators at the inhibitory gamma-aminobutyric acid (GABA)(A) receptor, the individual agents have different efficacy profiles and pharmacokinetic and pharmacodynamic properties, some of which differ significantly. The conventional BZDs clonaz …
Although all BZDs act as allosteric modulators at the inhibitory gamma-aminobutyric acid (GABA)(A) receptor, the individual agents have diff …
Pharmacological and clinical implications of local anaesthetic mixtures: a narrative review.
Nestor CC, Ng C, Sepulveda P, Irwin MG. Nestor CC, et al. Anaesthesia. 2022 Mar;77(3):339-350. doi: 10.1111/anae.15641. Epub 2021 Dec 14. Anaesthesia. 2022. PMID: 34904711 Free article. Review.
The additive itself or its preservative can have neurotoxic (adrenaline, midazolam) and/or chondrotoxic properties (non-steroidal anti-inflammatory drugs). ...
The additive itself or its preservative can have neurotoxic (adrenaline, midazolam) and/or chondrotoxic properties (non-steroidal ant …
Remimazolam - current knowledge on a new intravenous benzodiazepine anesthetic agent.
Kim SH, Fechner J. Kim SH, et al. Korean J Anesthesiol. 2022 Aug;75(4):307-315. doi: 10.4097/kja.22297. Epub 2022 May 19. Korean J Anesthesiol. 2022. PMID: 35585830 Free PMC article. Review.
Intravenous anesthetic agents such as midazolam, propofol, and ketamine are routinely used to provide anesthesia and sedation. ...This review aims to provide an overview of the basic and clinical pharmacology of remimazolam and to compare it with midazolam and propo …
Intravenous anesthetic agents such as midazolam, propofol, and ketamine are routinely used to provide anesthesia and sedation. ...Thi …
Midazolam: a review of therapeutic uses and toxicity.
Nordt SP, Clark RF. Nordt SP, et al. J Emerg Med. 1997 May-Jun;15(3):357-65. doi: 10.1016/s0736-4679(97)00022-x. J Emerg Med. 1997. PMID: 9258787 Review.
Midazolam is often employed as an induction agent for rapid sequence endotracheal intubation. ...Midazolam is a safe and effective agent for providing sedation in the emergency department....
Midazolam is often employed as an induction agent for rapid sequence endotracheal intubation. ...Midazolam is a safe and effec …
Dexmedetomidine versus Midazolam in Procedural Sedation. A Systematic Review of Efficacy and Safety.
Barends CR, Absalom A, van Minnen B, Vissink A, Visser A. Barends CR, et al. PLoS One. 2017 Jan 20;12(1):e0169525. doi: 10.1371/journal.pone.0169525. eCollection 2017. PLoS One. 2017. PMID: 28107373 Free PMC article. Review.
OBJECTIVES: To systematically review the literature comparing the efficacy and safety of dexmedetomidine and midazolam when used for procedural sedation. MATERIALS AND METHODS: We searched MEDLINE, EMBASE and COCHRANE for clinical trials comparing dexmedetomidine and mi …
OBJECTIVES: To systematically review the literature comparing the efficacy and safety of dexmedetomidine and midazolam when used for …
875 results