Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 2
1990 5
1991 1
1992 6
1993 10
1994 5
1995 7
1996 7
1997 10
1998 16
1999 18
2000 18
2001 18
2002 22
2003 24
2004 37
2005 25
2006 43
2007 39
2008 46
2009 69
2010 70
2011 82
2012 103
2013 121
2014 124
2015 130
2016 106
2017 95
2018 95
2019 100
2020 117
2021 144
2022 136
2023 120
2024 34

Text availability

Article attribute

Article type

Publication date

Search Results

1,749 results

Results by year

Filters applied: . Clear all
Page 1
Magnesium and Pain.
Shin HJ, Na HS, Do SH. Shin HJ, et al. Nutrients. 2020 Jul 23;12(8):2184. doi: 10.3390/nu12082184. Nutrients. 2020. PMID: 32718032 Free PMC article. Review.
In terms of antinociceptive action, the main mode of action of magnesium involves its antagonist action at the N-methyl-d-aspartate (NMDA) receptor, which prevents central sensitization and attenuates preexisting pain hypersensitivity. Given the pivotal function of NMDA …
In terms of antinociceptive action, the main mode of action of magnesium involves its antagonist action at the N-methyl-d-aspartate (NMDA …
Nonketotic Hyperglycinemia: Insight into Current Therapies.
Nowak M, Chuchra P, Paprocka J. Nowak M, et al. J Clin Med. 2022 May 27;11(11):3027. doi: 10.3390/jcm11113027. J Clin Med. 2022. PMID: 35683414 Free PMC article. Review.
So far, no causal treatment of NKH is known. Currently, the therapy is based on sodium benzoate and NMDA (The N-methyl-D-aspartate receptor) receptor site antagonists (dextromethorphan, ketamine). ...
So far, no causal treatment of NKH is known. Currently, the therapy is based on sodium benzoate and NMDA (The N-methyl-D-aspartate re …
A comprehensive review of opioid-induced hyperalgesia.
Lee M, Silverman SM, Hansen H, Patel VB, Manchikanti L. Lee M, et al. Pain Physician. 2011 Mar-Apr;14(2):145-61. Pain Physician. 2011. PMID: 21412369 Free article. Review.
Of these, the central glutaminergic system is considered the most common possibility. Another is the hypothesis that N-methyl-D-aspartate (NMDA) receptors in OIH include activation, inhibition of the glutamate transporter system, facilitation of calcium regulated intracell …
Of these, the central glutaminergic system is considered the most common possibility. Another is the hypothesis that N-methyl-D-aspartate ( …
Structure, function, and pharmacology of NMDA receptor channels.
Vyklicky V, Korinek M, Smejkalova T, Balik A, Krausova B, Kaniakova M, Lichnerova K, Cerny J, Krusek J, Dittert I, Horak M, Vyklicky L. Vyklicky V, et al. Physiol Res. 2014;63(Suppl 1):S191-203. doi: 10.33549/physiolres.932678. Physiol Res. 2014. PMID: 24564659 Free article. Review.
There is great interest in developing clinically relevant NMDA receptor antagonists that would block excitotoxic NMDA receptor activation, without interfering with NMDA receptor function needed for normal synaptic transmission and plasticity. This review summ …
There is great interest in developing clinically relevant NMDA receptor antagonists that would block excitotoxic NMDA receptor …
Structure, function, and allosteric modulation of NMDA receptors.
Hansen KB, Yi F, Perszyk RE, Furukawa H, Wollmuth LP, Gibb AJ, Traynelis SF. Hansen KB, et al. J Gen Physiol. 2018 Aug 6;150(8):1081-1105. doi: 10.1085/jgp.201812032. Epub 2018 Jul 23. J Gen Physiol. 2018. PMID: 30037851 Free PMC article. Review.
NMDA-type glutamate receptors are ligand-gated ion channels that mediate a Ca(2+)-permeable component of excitatory neurotransmission in the central nervous system (CNS). ...NMDA receptors exist as a diverse array of subtypes formed by variation in assembly of seven …
NMDA-type glutamate receptors are ligand-gated ion channels that mediate a Ca(2+)-permeable component of excitatory neurotransmission …
Brain NMDA Receptors in Schizophrenia and Depression.
Adell A. Adell A. Biomolecules. 2020 Jun 23;10(6):947. doi: 10.3390/biom10060947. Biomolecules. 2020. PMID: 32585886 Free PMC article. Review.
Here, we describe the temporal mechanisms implicated in schizophrenia-like and antidepressant-like effects of NMDA blockade in rats, and postulate that such effects may indicate that NMDA receptor antagonists induce similar mechanistic effects, and only the basal pr …
Here, we describe the temporal mechanisms implicated in schizophrenia-like and antidepressant-like effects of NMDA blockade in rats, …
Synaptic memory and CaMKII.
Nicoll RA, Schulman H. Nicoll RA, et al. Physiol Rev. 2023 Oct 1;103(4):2877-2925. doi: 10.1152/physrev.00034.2022. Epub 2023 Jun 8. Physiol Rev. 2023. PMID: 37290118 Free PMC article. Review.
The collective literature impels us to propose a relatively simple model for synaptic memory involving the following steps that drive the process: 1) Ca(2+) entry through N-methyl-d-aspartate (NMDA) receptors activates CaMKII. 2) CaMKII undergoes autophosphorylation result …
The collective literature impels us to propose a relatively simple model for synaptic memory involving the following steps that drive the pr …
Ketamine treatment for refractory anxiety: A systematic review.
Tully JL, Dahlén AD, Haggarty CJ, Schiöth HB, Brooks S. Tully JL, et al. Br J Clin Pharmacol. 2022 Oct;88(10):4412-4426. doi: 10.1111/bcp.15374. Epub 2022 May 20. Br J Clin Pharmacol. 2022. PMID: 35510346 Free PMC article. Review.
Ketamine is a noncompetitive antagonist of the N-methyl-d-aspartate (NMDA) glutamate receptor, which underlies its induction of pain relief and anaesthesia. However, the role of NMDA receptors in anxiety reduction is still relatively unknown. ...
Ketamine is a noncompetitive antagonist of the N-methyl-d-aspartate (NMDA) glutamate receptor, which underlies its induction of pain …
1,749 results