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SZ reduced JDN Rev, trimodal genotype distribution accounted for by polymorphism at 108/158, d1 increase excitability of GABA neurons, GABA neurons expressed in PFC (see above), SCHIZOPHRENIA manifests in Cognitive Symptoms, Neuropathology approached from autopsy, Heriability Rates shows importance of Environment, COMT inactivates post-synaptic catechols, atypical antipsychotics e.g. clozapine, d1 facilitate NMDA transmission, ERD receptors involved in migration of GABA neurons