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This Concept Map, created with IHMC CmapTools, has information related to: Antibiotics, Clindamycin inhibit 50S Subunit, Prokaryotic Biochemical Targets that Differ from those in Eukaryotic Cells such as DNA-dependent-RNA polymerases, Ribosomes including 30S Subunit, Spectinomycin is used as alternative drug for Gonorrheal infections, Rifamycin derivatives forms a stable complex with DNA-dependent-RNA polymerases, Beta-Lactams include Monobactams & Carbapenems, Quinolones such as Fluoroquinolones (-floxacin's), Bacitracin is usually given topically, Cephalosporins are resistant to beta-lactamase, Prokaryotic Biochemical Targets that Differ from those in Eukaryotic Cells such as Cell Walls, Vancomycin inhibits murien polymer synthesis (transglycosidase) Cell Walls, Chloramphenicol inhibit 50S Subunit, Beta-Lactams include Penicillins, Prokaryotic Biochemical Targets that Differ from those in Eukaryotic Cells such as Ribosomes, Tetracyclines (-cyclines) bind reversibly to 16S 30S Subunit, Beta-Lactams inhibit transpeptidase Cell Walls, ANTIBIOTIC MECHANISMS OF ACTION Act on Prokaryotic Biochemical Targets that Differ from those in Eukaryotic Cells, Rifamycin derivatives such as Rifabutin, Beta-Lactams include Cephalosporins, Tetracyclines (-cyclines) accumulate in bacteria, but not mammalian cells broad spectrum bacteriostatic