WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: tale of two infants, Baby 1 presents fasting, 30 mg/dl hypoglycemic suggests aldolase B deficiency, glycogen in liver cleaved by glycogen phosphorylase to release glucose 1-P, glycogen phosphorylase not activated, glucose not released in fasting, contributes to 30 mg/dl hypoglycemic, sucrose cleaved by sucrase to fructose in cytosol, Baby 1 presents 30 mg/dl hypoglycemic, protein kinase activity causes phosphorylation and activation of glycogen phosphorylase, hyperuricemia caused by uric acid, glucose 6-P in muscle enters glycolysis, glycogen phosphorylase acts on glycogen in liver, decreased inorganic phosphate leads to decrease in ATP, pyruvate in cytosol during aneorobic respiration converted to lactate, reducing sugar in urine suggests aldolase B deficiency, glycolysis produces pyruvate, lactate normally enters gluconeogenesis pathway in liver and ultimately converted to glucose by glucose 6-phosphatase, glucose 6-P when in excess, converted in glycolysis pathway in liver to lactate, pyruvate in mitochondria eneters TCA cycle, TCA cycle intermediates enter ETC, fructose 1-P in cytosol normally cleaved by Aldolase B, increased AMP degradation may also lead to lactic acidemia