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This Concept Map, created with IHMC CmapTools, has information related to: Naloxone, Reverses effects of opioids Action Increases pain sensation, Naloxone Indications Suspected opioid overdose, Reversal of opioid induced depression eg. respiratory depression, sedation or hypotension Route IV (onset of action 1-2min), Opioid receptors Action Competes for same recptor sites as opioids/narcotics, Increases respiratory rate Metabolised Liver, IV (onset of action 1-2min) Receptor Opioid receptors, Naloxone Indications Reversal of opioid induced depression eg. respiratory depression, sedation or hypotension, Liver Excreted Kidneys, Competes for same recptor sites as opioids/narcotics Which Reverses effects of opioids, Liver Excreted Biliary, Reverses effects of opioids Action Increases respiratory rate, Reverses effects of opioids Action Increases heart rate and BP