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This Concept Map, created with IHMC CmapTools, has information related to: Lignocaine, Neuronal signal propagation Prevents Pain signal propogation, Heart rate Metabolised Liver, Ventricular arrhythmias where amiodorone cannot be used IV - onset immediate Bolus 50-100mg (1 to 1.5mg/kg) 3-5 minutely or till arrhythmia subsides, Na+ channels Blocks Neuronal signal propagation, Liver Excreted by Kidneys primarily as metabolites, Na+ channels Decreases Myocardial action potential depolarisation, Bolus 50-100mg (1 to 1.5mg/kg) 3-5 minutely or till arrhythmia subsides Blocks Na+ channels, Lignocaine Class 1B antidysrhythmic agent Indications Local or regional anaesthesia, Lignocaine Class 1B antidysrhythmic agent Indications Prophylaxis in the setting of recurrent VF/VT, Lignocaine Class 1B antidysrhythmic agent Indications Ventricular arrhythmias where amiodorone cannot be used, Anaesthestic effects Metabolised Liver, Myocardial action potential depolarisation Which leads to Fewer action potentials, Pain signal propogation Therefore Anaesthestic effects, Fewer action potentials Decreased/reverted Heart rate