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This Concept Map, created with IHMC CmapTools, has information related to: immunosupress organ transplant Rx, Conventional types calcineurin inhibitor, Conventional types mTor inhibitor, Conventional types antimetabolites, everolimus mech T cell growth arrested at G1 to S phase (mammalian target of rapamycin), mycophenolate mofetil use for organs renal & cardiac, prednisone treats autoimmune diseases (Crohn's, SLE, psoriasis), alemtuzumab cytotoxic T cells, Polyclonal anti-thymocyte types anti-thymocyte globulin, antibody reagents types IL2 receptor antagonist, prednisone inhibit phospholipase A2 & downreg. expression of COX-2 (not COX-1), inhibits protein phosphatase that activates T cells (NFAT stays phosphorylated) dec. IL2 secretion, Conventional types Corticosteroids, Monoclonal anti-thymocyte type alemtuzumab, mTor inhibitor imp point myelosuppression (not nephrotoxic), basiliximab restricts activation & prolif. of T cells T cells, antibody reagents types Monoclonal anti-thymocyte, antibody reagents results in T cell depleting, tacrolimus bind to immunophilins (FKBP or cyclophylin), Corticosteroids type prednisone, mTor inhibitor types sirolimus