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This Concept Map, created with IHMC CmapTools, has information related to: GI Wk 3 Esophagus and Stomach, luminal pressure different in esophageal body, Mucosa Epithelium, luminal pressure can be measured by manometry, Esophagus innervation, Esophagus arrives via lower esophageal sphincter at Stomach, Mucosa Epithelium, pepsinogen from chief cells, 5 different cell types Mucus cell, gastrin from G cells, Histology of the Esophagus and Stomach Esophagus, Mucosa Lamina propria, gastrin functions to stimulate acid secretion from parietal cells, Stomach Submucosa, Muscularis externa Two layers of muscle. Inner layer = circularly arraged, for squeezing the lumen shut. Outer layer = longitudinally arranged for shortening the esophagus. Home of Auerbach's (myenteric) plexus*, Stem cells Located near the neck of the glands of the stomach. Migrate upwards (mucus cell) or downwards (chief/parietal cell) following differentiation., Pharynx 2 UES, Mucus cell Line the stomach and secrete mucus to protect the epithelium from damage due to the acidic environment. Notice the apically located mucus-containing granules, Epithelium Simple columnar cells., Epithelium Lamina propria, Swallowing changes luminal pressure