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This Concept Map, created with IHMC CmapTools, has information related to: Week 10, Asthma, Acute & Chronic Clinical Presentation, Arterial Blood Gases Metabolic Acidosis, Physiology Effect on Arterial Blood Gases, Smooth Muscle Spasm G-Coupled Protein Receptor M3 Receptor, 2,727.27 mg per dose In mL 54.55ml, Beta-2 vs Beta-1 Beta-2 In lungs and uterine muscles: -Causes dilation in lungs -Causes mucus clearance (both are necessary during asthma attack), Physiology Asthma Attack Smooth Muscle Spasm, 0.15 mg/kg/dose every 20 minutes for 3 doses Dose for our 120 lb patient 1.636mL per dose = 4.9mL total, Clinical Presentation Symptoms Shortness of breath, Alkalosis Decreased PaCO2, FEF25-75 is Decreased, Acidosis Decreased HCO3, M1 vs M2 vs M3 M2 In heart: -Slow HR -Slow depolarization -Reduce contractile forces in atrium -Reduction conduction speed in SA Node, Alkalosis Increased pH, Asthma, Acute & Chronic Case Asthma Stage End of Stage 3 beginning of Stage 4, Hydrocortisone Glucocorticoid Receptor Bronchodilation, inhibits inflammatory response increases -bronchodilation -mucus clearance, Oxygen Dosing 40-60% oxygen if patient has hypoxaemia with PaCO2 < 5.3 kPa, FEV1 Moderate 50-65%, inhibits acetylcholine causes -anticholinergic bronchodilation -decreases volume of respiratory secretion