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This Concept Map, created with IHMC CmapTools, has information related to: Week 11, Acetylcholine Receptors Causes Muscle Contraction, Patient Information 20 YOF 110lbs Case Symptoms Trouble swallowing food, Treatment Options Option #2 Edrephonium (Tesilon), Single Fiber EMG Measures Action Potentials (via concentric needle EMG electrode to stimulate), Treatment Options Other Options Treating immune response, Temporarily reduces muscle weakness Used Good diagnostic tool, Diagnostic Procedures Hand Shake Test, Neostigmine (Prostigmin) Long Duration of Action, 0.1-0.5 mg/kg If patient is responsive to treatment Reduces muscle weakness, 25 mg PO Q8h Daily Dose 75 mg per day, Serum Antibodies Majority of MG patients have many types of antibodies including forms directed against acetylcholine receptor and muscle-specific receptor tyrosine kinase, Hand Shake Test Patient cannot continue to grip during handshake, Edrephonium Dose 5 mg IV, Diagnostic Procedures Electromyography (Repetitive Nerve Stimulation), Treatment Options Option #3 Pyridostigmine (Mestinon), Treating immune response Medications Prednisone, Neostigmine (Prostigmin) MOA Inhibts Acetlycholinesterase, Patient Information 20 YOF 110lbs Treatment Options Neostigmine, 5 mg IV 0.5 mg/ml 10 ml IV, Acetylcholinesterase inhibitor increases Concentration of Acetylcholine