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This Concept Map, created with IHMC CmapTools, has information related to: Big Cmap, Muscle weakness for 1 month Correlates with Experiences severe muscle fatigue & weakness (Chronic), Neuromuscular Blockers Depolarizing Succinylcholine, Cholinergic Syndrome experience the following symptoms salivation and sweating, Pralidoxime Bolus 1g in 30 minutes, Sodium channels Inhibits Transmission of pain signaling, Atropine (Muscaric Effect Treatment) dose Adult: 2-5mg IV, repeated every 5 minutes doubling the initial dose, Atropine Test inject 0.6-1 mg IV, CNS Effect Treatment Give Oxygen, Obidoxime ???? 0.25mg, 0.6-1 mg IV Indication Skin flushing develops, Patient: 20 yo F Weight: 110lbs (50kg) Height: 5'6 Maintenance dose Neostigmine (Prostigmin 15mg) 0.5mg/kg, Neostigmine 0.1mg/kg Initial IV 5mg (10mL) of 5mg/10ml vial, Inhibition of ACh-esterase activity, increasing [ACh] Saturates leftover receptors with ACh Nicotinic Receptors (ACh Substrate), Acetylcholine Disorders ???? Female black widow spider Latrodectus mactrans, Cholinergic Syndrome experience the following symptoms miosis, Neuromuscular Blockers Nondepolarizing d-Tubocurarine, Cholinergic Syndrome If uncertain of OGP poisoning Atropine Test, Acetylcholine Disorders ???? Snake Venom, Droopy eyelids for about 3 months Correlates with "droopy" eyelid/weakened facial expressions, Smooth Muscle (N2 or NN) Symptoms Difficulty swallowing/breathing