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This Concept Map, created with IHMC CmapTools, has information related to: Arterial Venous Disease Thrombosis, Patient JE Information 250 lb, Endothelial Dysfunction causes Increased Local Mediators, Pharmacological Treatment of Clotting Disorders includes Anticoagulants (Rx arterial & venous thrombosis), Truck Driver Stopped 6 months ago, Ramipril 10mg QD Decreases Angiotensin II, Patient JE Complains of cramping, pain, tired legs or hip muscles that worsens during walking/activity and subsides with rest, Vascular Physiology Normal Normal Vascular Physiology, Aspirin PRN Pt should not take High Dose, Oxidative Stress caused by Hyperlipidemia, Arterial Insufficiency/PAD Manifestations Slow healing wounds, Vascular Physiology Venous Venous Insufficiency/PVD, Platelet Aggregation Decreases CV Events, High LDL classified as Hyperlipidemia, Warfarin 5mg QD Counseling point Patient should use a soft bristle toothbrush, Patient JE Current Meds Ramipril 10mg QD, COX-2 Increases Platelet Aggregation, Patient JE Information 54 YOM, Venous Insufficiency/PVD Manifestations Deep Vein Thrombosis, High Dose Inhibits COX-2, Blocking the regeneration of vitamin K, inhibiting vitamin K-dependent clotting factors II (prothombin), VII, IX, and X Decreases Blood coagulation