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This Concept Map, created with IHMC CmapTools, has information related to: Lymphatic System cMAP (immuno), Open-System Primary organs Thymus, Bone Marrow (BM) eliminate self-reactive B cells, Spleen Appendix Lymph Nodes Tonsils Adrenoid MALT, Thymus 95% thermocytes die because -Cannot recognize any Ag -Are self-reactive, Collecting vessels afferent fluid to lymph node, Secondary Follicles thick mantle non-dividing B-cells interspersed with: -Macrophages -T cells -Follicular DCs, Collecting vessels efferent blood to heart, Open-System Primary organs Bone Marrow (BM), Spleen Appendix Lymph Nodes Tonsils Adrenoid lymph nodes Follicles, Primary Follicles comprised of Follicular DCs & Resting State B cells, Bone Marrow (BM) Stromal Cells Provide Cytokines, Follicles 2 types Primary Follicles, Bone Marrow (BM) maturation occurs in direction of Central Vein, Central Vein pic, Thymus Nurse cells develop T cells, MALT less organized than spleen & lymph nodes, Lymphatic System organs Open-System, Follicular DCs & Resting State B cells Ag binds Secondary Follicles, Follicular DCs & Resting State B cells Ag doesn't bind or are self-reactive B cell death, Open-System Tertiary organs Collecting vessels