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This Concept Map, created with IHMC CmapTools, has information related to: BPAidp, Chromosomal abberations type Structural, Structural Common types Insertions, deletions, inversions, translocations, Numerical Such as Polyploidy, Predisposition to certain cancers Namely Breast cancer, Mimics natural estrogen molecules Binds to Natural estrogen receptors, Numerical Such as Aneuploidy, Chromosomal abberations Caused by Double-strand break repair machinery interruption, Cytotoxicity Causes Mimics natural estrogen molecules, Cell metabolism ailments Toxic concentration gg, Cytotoxicity Causes Cell metabolism ailments, Cell metabolism ailments Benign concentration =< 0.25mM, Genotoxicity Occurs at gg, Bisphenol A (BPA) is a chemical compound used in plastics. What are the molecular mechanisms of action of BPA? What is the impact on the cellular level? Predisposition to certain cancers, Abnormal karyotypes Causes General genomic instability, Interuption of chromosomal replication/repair mechanisms Results in Abnormal karyotypes, Chromosomal abberations type Numerical, Natural estrogen receptors Linked to Breast cancer, Bisphenol A (BPA) is a chemical compound used in plastics. What are the molecular mechanisms of action of BPA? What is the impact on the cellular level? Cytotoxicity, Genotoxicity Causes Interuption of chromosomal replication/repair mechanisms, Mimics natural estrogen molecules Reffered to as Xeno-estrogen